Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIVISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGARVSYPVLNVKVFLENGEVK-IFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVSTPTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRNDYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE 5DHQ Chain:B ((32-266)) ------------------------------------DDVEPEIVISIGGDGTFLSAFHQYEERLDEIAFIGIHTGHLGFYADWRPAEADKLVKLLAKG--QKVSYPLLKTTVKY----KEATYLALNESTVKSSG-PFVVDVVINDIHFERFRGDGLCMSTPSGTTAYNKSLGGALMHPSIEAMQLTEMASINNRVYRTIGSPLVFPKHHVVSLQPVNDKDFQISVDHLSILHRDVQEIRYEVSAKKIHFARFRSF-PFWRRVHDSFIEDLE-

General information: TITO was launched using: RESULT: Template: 5DHQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1169 -32001 -27.37 -140.97 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain B : 0.84 3D Compatibility (PKB) : -27.37 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.427

(partial model without unconserved sides chains): PDB file : Tito_5DHQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DHQ-query.scw PDB file : Tito_Scwrl_5DHQ.pdb: