Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTDNATILQHVPVGKKVGIAFSGGLDTSAALLWMKQK-GAEPYAYTANLGQPDEDDYDAIPKKAEQYGAVKARLIDCRLQLALEGI-AAIQCGAFHISTGGVPYFNTTPLGRAVTGTMLVTAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQNFIDELGGRAEMSQFLIDNGFDYKMSKEKAYSTDSNMLGATHEAKDLEYLNAGIKIVDPIMGVAFWKEEVEIKPEEVTIRFEEGVPVALNGQRFDNPVELILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDSQALMLRETAQRWVAKAITGEVTLELRRGNDYTIMNTESPNLTYEAERLTMEKGDSMFTPMDRIGQLTMRNLDITDTRAKLGIYTDAGLLSIGQGSALPQLDNKKK 1KOR Chain:C ((1-391)) --------------MKIVLAYSGGLDTSIILKWLKETYRAEVIAFTADIGQG--EEVEEAREKALRTGASKAIALDLKEEFVRDFVFPMMRAGAVY----EGYYLLGTSIARPLIAKHLVRIAEEEGAEAIAHGATGKGNDQVRFELTAYALKPDIKVIAPWREWSF----QGRKEMIAYAEAHGIPVP-----PYSMDANLLHISYEGGVLEDPWAEPPKGMFRMTQDP--EEAPDAPEYVEVEFFEGDPVAVNGERLS-PAALLQRLNEIGGRHGVGRVDIVENRFVGMKSRGVYETPGGTILYHARRAVESLTLDREVLHQRDMLSPKYAELVYYGFWYAPEREALQAYFDH-VARSVTGVARLKLYKGNVYVV-GRKAPKSLYRQDLVSF-----GYDQKDAEGFIKIQALRLRVRA----------------------------

General information: TITO was launched using: RESULT: Template: 1KOR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 2005 -321 -0.16 -0.84 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain C : 0.71 3D Compatibility (PKB) : -0.16 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.391

(partial model without unconserved sides chains): PDB file : Tito_1KOR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KOR-query.scw PDB file : Tito_Scwrl_1KOR.pdb: