Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAMLPEWTTACPDWEERIVAKKSLMPCEPLFPQVADVAERIFKELILVDVMGSPKMGDVTLDWVIEFVRAIFGSYNPNTKRRLIREFFLLISKKNTKSTIAAGVMLVALLLNDRLSAELIILAPTKEVADNSFNPIRDFIRADEELSAMINVSEHTKTVTHLGTGATLKVIAAESNAAAGKKASIILIDEVWLFGKRANAESMFREAKGGLASRPEGCVIYLSTMSDEVPCGVFKQLLDYARDVRDGIKEDKGFLPLIYEFP-KRLVEAGEHLKPEHFYITNPNLGASVDLEYLISEFKKVKDAGEESLRDFLAKHLNIEIGMNLRA-NRWAGAEYWNKQKHVFGLDQLIEQSDVITIGIDGGGLDDLLGYAVLGRLKKDPRVWWLWNHAWANKIALERRKENIPKYDDFKLEGSLTVVDRVGDDIDQLAAIAKKVYDSGKLNKIGLDPLGLGGLLDGLLEAGIPEESMFAVPQGYKLMSYILTTERKLAEGNLYHAGQQLMT-WAAGNARVVMVGN-GMRITKQESGVGKIDPLIATFNAVALMSMNPEPTNKEYNVFFV 5HHY Chain:A ((1-385)) LLVTPPKALLKPLSIPNQLL----------LGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRNP---------LTLVISGS-------GHCALEAALVNVLEPGDSFLVGANG-----------IWGQRAVDIGERIGARVHPMT---KDPGGHYTLQEVEEGLAQHKPVLLFLT----------HGES--------------------ST-------GVLQPL--------------DGFGELCHRYKCLLLVDSVASLGGTPLYMDRQG----IDILYSGSQ-----------------KALNAPPGTSLISFSDKAKKKMYSRKTKPF------------SFYLDIKWLANFWGC------DDQPR---MYHH-------------TIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHGRLQALGLQLFVKDPALR------LPTVTTVAVPAGY--------DWRDIVSYVIDHFDIEIMGGLGPSTGKVLRIGLLGCNAT---------RENVDRVTEALRAALQHCPKK--------

General information: TITO was launched using: RESULT: Template: 5HHY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2257 -54389 -24.10 -142.75 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -24.10 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.282

(partial model without unconserved sides chains): PDB file : Tito_5HHY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5HHY-query.scw PDB file : Tito_Scwrl_5HHY.pdb: