Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKLIVLSNRISMPSGK---------ASAGGLAVAVQDALNDSNGIWLGWNGQQITDTEAPEFDQAYSHGIDYITCPLTHQQYAQYYCGFANKVLWPAMHDRDDLIEYNAEEYNTYQKVNRLFAEKLQQIAQPDDLIWVHDYHFFSVARHCR-ELGMQNK---IGFFLHIPFASLNIWRKIPVALQLVQDLCQYDVIGLQTQTDQNTCMQTCMGLLEAQKILSDRISYKKRQILIKSYPIGV----------QPELIQRQAQQAFHTPYVFNFEDIPRQKTIIGVDRIDYSKGLLERFNAFATFLETNPEYHGLVRHLQVATPSRTDIPAYQRLYQRFKAKLELINEEFAHEDWRPIDCCFDTVQHDSLMHIYRRSDICWISSLRDGMNLVAKEYIAAQDPENPGVLILSKYAGAAEQMTQALIVDPLDRAAMMDSLKTALEMSKAERINRYEQLIEGLAATDLSDWRNNFLKDLENSPTFTKSKLSLQEKYQPTYHAL 5HVL Chain:B ((4-467)) -GKVLVVSNRIPVTIKRLDNGSYDYSMSSGGLVTALQGLKKTTEFQWYGWPGLEIPEDEQTKVNDELKSKFNCTAIFLSDTIADLHYNGFSNSILWPLFHYHPGEMNFDENAWAAYIEANKKFALEIVKQVNDDDMIWVHDYHLMLLPEMLRQEIGNKKKNIKIGFFLHTPFPSSEIYRILPVRKEILEGVLSCDLIGFHTYDYARHFISSVSRIVPNVSTLPNGIKYQGRSISIGAFPIGIDVDNFIDGLKKDSVVERIKQLKS------KFKDV---KVIVGVDRLDYIKGVPQKLHAFEVFLNENPEWIGKVVLVQVAVPSRGDVEEYQSLRSTVSELVGRINGEFGTVEFVPIHYLHKSIPFDELISLYNISDVCLVSSTRDGMNLVSYEYIACQQ-DRKGVLILSEFAGAAQSLNGALIVNPWNTEDLSEAIKESLTLPEEKREFNFKKLFTYISKYTSGFWGESFVKEL------------------------

General information: TITO was launched using: RESULT: Template: 5HVL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2339 -5434 -2.32 -12.32 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain B : 0.76 3D Compatibility (PKB) : -2.32 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.560

(partial model without unconserved sides chains): PDB file : Tito_5HVL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5HVL-query.scw PDB file : Tito_Scwrl_5HVL.pdb: