Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTFVVTENCIKCKYQDCVEVCPVDCFYEGPNFLVINPDECIDCALCEPECPANAIFSEDELPEGQEVFIELNAELSQKWPNITQIGEQPADREEWNGKPDKLQYLEK 1B0V Chain:B ((1-106)) -AFVVTDNCIKCKYTDCVEVCPVDCFYEGPNFLVIHPDECNDCALCEPECPAQAIFSEDEVPEDMQEFIQLNAELAEVWPNITEKKDPLPDAEDWDGVKGKLQHLER

General information: TITO was launched using: RESULT: Template: 1B0V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 521 -72876 -139.88 -687.51 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain B : 0.89 3D Compatibility (PKB) : -139.88 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.89 QMean score : 0.477

(partial model without unconserved sides chains): PDB file : Tito_1B0V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1B0V-query.scw PDB file : Tito_Scwrl_1B0V.pdb: