Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ----MSHTQL-IKDTLNILDL--NIYFEENCLTKEKYKGQICLIYKGTLLYKPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVA-DTSVAEKHCF-----ISQKVRWSVI-A-RLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQTLPKVLCFDEFKSVRSVASAMSFIMMDGQSH-----------ALLDIVENRRLPYLERYFSRFSLATREAVQLIVIDMYAPYVSLVKKLFPECSVDHRSFPHRPTYWQNFLESSSERNHGTT------- 1M6Y Chain:A ((4-296)) RKYSQRHIPVMVREVIEFLKPEDEKIILDCTVGEGGHSRAILEHCPGCRIIGIDVDSEVLRIAEEKLKEFSDR-VSLFKVSYREADFLLKTLGIE------KVDGILMDLGVSTYQLKGENRGFTFEREEPLDMRMDLESEVTAQKVLNEL--PEEELARIIFEYGEEKRFARRIARKIVENRPLNTTLDLVKAVREALPSYEIRRRKRHFATKTFQAIRIYVNRELENLKEFLKKAEDLLNPGGRIVVISFHSLEDRIVKETFRN-SKKLRILTEKPVRPSEEEIRENPRARSGRLRAAERI

General information: TITO was launched using: RESULT: Template: 1M6Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1348 31395 23.29 120.75 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 23.29 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.212

(partial model without unconserved sides chains): PDB file : Tito_1M6Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1M6Y-query.scw PDB file : Tito_Scwrl_1M6Y.pdb: