Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNSQDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSL-STVMYNPKILSHSVQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEIDHINGVMFYDHINDQNPFALKEGVLVIE 1VEY Chain:B ((5-167)) ------ILRMGDPILRKISE----PVTEDEIQT-KEFKKLIRDMFDTMRHAE-----GVGLAAPQIGILKQIVVVGSEDNERYPGTPDVPERIILNP-VITPLTKDTS-GFWEGCLSVP-GMRGYVERPNQIRMQWMDEKGNQFDETIDGYKAIVYQHECDHLQGILYVDRLKDTKLFGFNE------

General information: TITO was launched using: RESULT: Template: 1VEY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 806 -34204 -42.44 -211.13 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain B : 0.78 3D Compatibility (PKB) : -42.44 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.471

(partial model without unconserved sides chains): PDB file : Tito_1VEY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VEY-query.scw PDB file : Tito_Scwrl_1VEY.pdb: