Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDPYTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQGIFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHTLPWGSKD--PDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEVDPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHIRFFPVDSYQMTDLPETAENIPYDTFAF-TPFMPKLNTANPEVQKYLLDIATYWIKEFDIDGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFTDSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKELMKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSLRKQLSKIISEGSTQWLIVYDREDKLY-FTRELEGQIIYVYFNQSKEPWVVEQENEVILSQNCQLLEDGKAEIRQYGFLIMC 1G1Y Chain:B ((1-541)) MLLEAIFHEAKGSYAYPISETQLRVRLRAKKGDVVRCEVLYADRYASPEEELAHAL--AGKAGSDERFDYFEALLECSTKRVKYVFLLTGPQGEAVYFGETGFSAERSKAGV-----FQYAYIHRSEVFTTPEWAKEAVIYQIFPERFANGDPSNDPPGTEQW-AKDARPRHDSFYGGDLKGVIDRLPYLEELGVTALYFTPIFASPSHHKYDTADYLAIDPQFGDLPTFRRLVDEAHRRGIKIILDAVFNHAGDQFFAFRDVLQKGEQSRYKDWFFIEDFPVSKTSRTN---------YETFAVQVPAMPKLRTENPEVKEYLFDVARFWMEQ-GIDGWRLDVANEVDHAFWREFRRLVKSLNPDALIVGAIWHDASGWLMGDQFDSVMNYLFRESVIRFFATGEIHAERFDAELTRARMLYPEQAAQGLWNLLDSHDTERFLTSCGGNEAKFRLAVLFQMTYLGTPLIYYGDEIGMAGATDPDCRRPMIWEEKEQNRGLFEFYKELIRLRHRLASLTRGNVRSWHA--DKQANLYAFVRTVQDQHVGVVLNNRGEKQTV-------------------------------

General information: TITO was launched using: RESULT: Template: 1G1Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2997 -70359 -23.48 -131.02 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain B : 0.81 3D Compatibility (PKB) : -23.48 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.453

(partial model without unconserved sides chains): PDB file : Tito_1G1Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1G1Y-query.scw PDB file : Tito_Scwrl_1G1Y.pdb: