Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----MAKCKKYEEFGLDSLLQETRGGRNHAYMT------VEQEKVFLARHLKATEAGEF-------------VTID-ALFQAYKKEL---GRSYTR-------DAFYQLLK-RHGWRNITPRPEHPRKA----DAQTIVAS--------KNKVSIQE-D-K 4QT6 Chain:A ((1-157)) GFDPEKAQCCLVEN---GQILTHGSGGKGYGLASTGVTSGCYQWKFYIVKENRGNEGTCVGVSRWPVHDFNHRTTSDMWLYRAYSGNLYHNGEQTLTLSSFTQGDFITCVLDMEARTISFGKNGEEPKLAFEDVDAAELYPCVMFYSSNPGEKVKICDMQMR

General information: TITO was launched using: RESULT: Template: 4QT6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 437 33546 76.76 310.61 target 2D structure prediction score : 0.36 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 76.76 2D Compatibility (Sec. Struct. Predict.) : 0.36 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.085

(partial model without unconserved sides chains): PDB file : Tito_4QT6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4QT6-query.scw PDB file : Tito_Scwrl_4QT6.pdb: