Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNFNIAKVMSIDQLETQIAELDNLPEHREIVTFMRRSAPLNTSQRTALEQHRDLILEYPVGDLRQHFEHPERPLTVEIGFGMGRSLVLM-AKANPERNYVGIEVHVPGIAQCVYEAGMAELKNLRVLDADAIQILREMPDNSINCVQLYFPDPWQKKRHFKRRFVIHERMQLVEQKLELGGTFHAATDWEPYAEWMLDVLDNRP-NLENLAGKGNSYPRPEWRPV-TKFERRGIESGHKINDFIFKKIK 1YZH Chain:A ((11-214)) ------------------GATELLEANPQYVVLNPLEAK---------------------AKWRDLFGND-NPIHVEVGSGKG-AFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTDYFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFEYSLVSFSQYGMKLNGVWL--DLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF--

General information: TITO was launched using: RESULT: Template: 1YZH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 984 -16534 -16.80 -82.26 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -16.80 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.441

(partial model without unconserved sides chains): PDB file : Tito_1YZH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YZH-query.scw PDB file : Tito_Scwrl_1YZH.pdb: