Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDNLNSPEQSDLSWLTIWSTFLNQAPFTAQTQAPEAACFLQQLIEASLQGDSCIDISPEQIETLGQ-L-----------------VI-SAEQ-AKSQVAPCVHDGQGLALYRYWNLEQRLAEQIRRLKQ-QPIQPVSCEEHLDL-----LTDPHQRTALQMVTRQSLSIITGGPGTGKTYTLARIIAVLSQA--IPHIRVAMAAPTGKAAQRMQEALQNSFNDPKLLESGLMSDELRNQSTQTIHRLLGMGHSQTPRFNQKQPLPYDVIVVDEASMLDLNLATLLFEAVPESCRIILLGDANQLASVDVGAVLADLQQIEAL-----------------------------SENRVHLQTSRRFAEGALIGQVARFIQMQTSQIDHEQVLQQFEIDIVQVSELRSIPLEADMPDVVQLEYLPEESPIALETYYQKLMVGFQGYVQSLKAYLQDDHSLEHIENIVKSFDDYRILTAVRHGPFGLQQLNQYAERWLQQQLGIVTLGGWYVGRPVMMTYNDYQLGISNGDIGLCFEHRTQPQQFEVYFPSLNKWVAANRLPKSIQSAFALTIHKSQGSEFTHTAVVLDQAAKNLLSQELIYTAITRAKKVVSLLVDPEALLQ-SFTVRTTRKSGLVEKVNRLVR 1W36 Chain:D ((26-606)) --------------------------TVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDE---QKKRIPEDASTLHRLL----------HAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKT-AVKTVFQQDFT-------------------DIEKRLLQSG--EDYIAMLEEALAGYGRYLDLLQA-------RAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKR------------------------------------------------------QPSRLPE-HETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERI-LSAAIATRTERRSGLAALFSS---

General information: TITO was launched using: RESULT: Template: 1W36.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 2050 23145 11.29 50.76 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain D : 0.70 3D Compatibility (PKB) : 11.29 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.379

(partial model without unconserved sides chains): PDB file : Tito_1W36.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1W36-query.scw PDB file : Tito_Scwrl_1W36.pdb: