Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHFFGCFLKYAFALKSIRLEDSPVHALEQKILTEGIVLSDQVLKVDAFLNHQIDPVLMQQIGKEFAARFKDAGITKIITIEASGIAPAIMAGLELGVPVIFARKYQSLTLKDDLYRAKVFSFTKQTESTIAISNKHINSSDKALVIDDFLANGQAALGLIDLIHQANAEVVGVGIVIEKSFQPGRDLLLEKGYRVESLARVQSLADGTVTFVKE 1L1Q Chain:A ((2-177)) --------------------TMSVADAHALIKTIPDFPTKGIAFKD-LSDILSTPAALDAVRKEVTAHYKDVPITKVVGIESRGFILGGIVANSLGVGFVALRKAGKLPG--DVCKCT-FDMEYQKGVTIEVQKRQLGPHDVVLLHDDVLATGGTLLAAIELCETAGVKPENIYINVLYEI-EALKGREKVGQKCTRLFSV-------------

General information: TITO was launched using: RESULT: Template: 1L1Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 919 -134985 -146.88 -766.96 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -146.88 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.381

(partial model without unconserved sides chains): PDB file : Tito_1L1Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1L1Q-query.scw PDB file : Tito_Scwrl_1L1Q.pdb: