Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----FDCYIERLQKEHMLSGMKAEP-----NKEAWIDGFEIWVYSNCRIHPT-ILPDGSIANGRFWSELDWFHTCEE------SESKSKSE------- 1JYR Chain:A ((1-96)) GSMAWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRD---GAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDI

General information: TITO was launched using: RESULT: Template: 1JYR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 222 12709 57.25 176.51 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 57.25 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.351

(partial model without unconserved sides chains): PDB file : Tito_1JYR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JYR-query.scw PDB file : Tito_Scwrl_1JYR.pdb: