Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence QCNHHLLYNGRHWGTIRKKAGWA---VRFYEEKPGQPKRLVTICKNASPVHCNYLKCTNLAAGFSAGTSTDVLS---SG---TV--GSIGNDPQAQRQ--------- 1QHO Chain:A ((408-495)) -------------GTTTQR--WINNDVYIYERKFFNDVVLVAINRNTQ----SSYSISGLQTALPNGSYADYLSGLLGGNGISVSNGSVASFTLAPGAVSVWQYSTS

General information: TITO was launched using: RESULT: Template: 1QHO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 213 8007 37.59 117.74 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : 37.59 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.353

(partial model without unconserved sides chains): PDB file : Tito_1QHO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QHO-query.scw PDB file : Tito_Scwrl_1QHO.pdb: