Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSFNRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGK--GVRRPAVWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQ--NRLWRKTRSRNPGSSCIGADPNRNWNASFAGKG-ASDNPCSEVYHGPHANSEVEVKSVVDFIQKH-----GNFKGFIDLHSYSQLLMYPYGYSVKK-APDA-EELDKVARLAAKALASVSGTEYQVGPTCTTVYPASGSSIDWAYD-NGIKFAFTFELRDTG-TYGFLLPANQIIPTAEETWLGLKTIMEHVRDNLY 3QNV Chain:A ((5-314)) ----------------------------------------------------------------------------------------------------------------------YDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMRDFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTMAQTNG--YTPQQAS-DLYITDGDMTDWAYGQHKI-FAFTFEMYPTSYNPGFYPPDEVIGRETSRNKEAVLYVAEKADC---

General information: TITO was launched using: RESULT: Template: 3QNV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1700 23498 13.82 79.38 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : 13.82 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.584

(partial model without unconserved sides chains): PDB file : Tito_3QNV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QNV-query.scw PDB file : Tito_Scwrl_3QNV.pdb: