Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WFVEDINRVQAEDLLYGKPDGAFLIRES-SKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYNLYSSLKELVLHY 1R1P Chain:D ((11-85)) WFHEGLSRHQAENLLMGKDIGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDTKGNYFLWTEK-FPSLNKLVDYY

General information: TITO was launched using: RESULT: Template: 1R1P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 255 -30430 -119.33 -411.21 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain D : 0.75 3D Compatibility (PKB) : -119.33 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.664

(partial model without unconserved sides chains): PDB file : Tito_1R1P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1R1P-query.scw PDB file : Tito_Scwrl_1R1P.pdb: