Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQARGY--KIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADAKIFW-AQLGL-------ESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA 4YB8 Chain:A ((2-137)) ----------NDLERLF-NPSAIAVVGASKDPSKIGSQILRNLLSYGFKGKVYPINPTAD--ELMGLKCYPKVSDVPDKVDVAVISVPSDKVLGVIDDCGKAGVKFAVVITSGFKEVGNEELEEELVRRAHSYG-MRVLGPNIFGYLYAP-----

General information: TITO was launched using: RESULT: Template: 4YB8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 626 -21355 -34.11 -169.48 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -34.11 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.620

(partial model without unconserved sides chains): PDB file : Tito_4YB8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YB8-query.scw PDB file : Tito_Scwrl_4YB8.pdb: