Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLAILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLL-YSIVS--LSLSGQSFSLLLVAFICLINLLSDTL-------SYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILGGVLLGILSIQFISLLNALT----------FLI--------------AFLGILF-IKTDLLKVEK-----------TINYQEGLSVKSFCQHLLQSSK-------LIWN----------MNKVLLVLFIISTSQAVINV--TVPVSTLFLRNQPFLNLQTGQSLALLSTFELSALIVGSLVSGYLQHTISIKTA----LYASLVIQLLLLVGFATVRFDWIL------IFSTLDAFFAGVLSPRLQELV----FKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL---FLLVAFVMLLNIRESI-- 5I6C Chain:A ((66-545)) -----------PFFGLNEKIPVLLAFILGLQHALAMLAGVVTPPLIISSSLS--LPSDLQQYLVSTSLIVCGLLSMVQITRFHIYKTPYYIGSGVLSVMGVSFSIISVASGAFNQMYSNGFCQLDEAGNRLPCPEAYGALIGTSACCALVEILLAFVPPKVIQKIFPPIVTGPTVMLIGISLIGTGFKDWAGGSACMDDGMLCPSATAPRPLPWGSPEFIGLGFLVFVSIILCERFGAPIMKSCSVVIGLLVGCIVAAACGYFSHADIDAAPAASFIWVKTFPLSVYGPMVLPIIAVFIICACECIGDVTATCDVSRLEVRGGTFESRIQGAVLADGINSVVAALATMTPMTTFAQNNVVIALTRCANRWAGYCCCLILIVAGIFAKFAAAIVAIPNSVMGGMKTFLFASVVISGQAIVAKAPFTRRNRFILTASMALGYGATLVPTWFGNVFPQTENRDLEGFENAIELVLETGFAVTAFVAMLLNAIMPAE

General information: TITO was launched using: RESULT: Template: 5I6C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2199 -317692 -144.47 -802.25 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -144.47 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.259

(partial model without unconserved sides chains): PDB file : Tito_5I6C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5I6C-query.scw PDB file : Tito_Scwrl_5I6C.pdb: