Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLDYLQALKRI-PEARGAWILHGQEPLLEQNLLDTFRKSWQQQD-IERQRYDISSVSDWKNVFNALNSLSLFSQQLAIEVHGNI-KPDANGLKQLKSYIQHN-ETNLLLIVLPKQDSSSLKSAFFQVVEANGVVVALTANYPQDRQRILAAEAEKLEIQLDNDAWQWLMQHHEHNLLAAKNSLMRVRDTFPDQKLIQIEQLYACLQDQSRYTTYDLSDALLEGNLAQSIKIFQYLIGSGEPESLILWTLSKEMRLLMQLFEQPHNALQLGIWKTKVSLYQQALRRLNPQQFLGWSALLLQIDAAIKGMSNENAQHLMQQAIAELCGKTLFIH 1JQL Chain:B ((2-139)) IRLYPEQLRAQLNEGLRAAYLLLGNDPLLLQESQDAVRQVAAAQGFEEHHTFSIDPNTDWNAIFSLCQAMSLFASRQTLLLLLPENGPNAAINEQLLTLTGLLHDDLLLIVRGNKLSKAQENAAWFTALANRSVQVTC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1JQL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 566 -9329 -16.48 -69.62 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain B : 0.59 3D Compatibility (PKB) : -16.48 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.437

(partial model without unconserved sides chains): PDB file : Tito_1JQL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JQL-query.scw PDB file : Tito_Scwrl_1JQL.pdb: