Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVSYSASYLPRMQQNLTLLQHYHENKENCMSFSMTKLSAALLLTSSLVGCAAVVKTPYQAPAVQVPGSFQYDKAKAKTASVEQYSDHWWTLFGDA-QLNQLVTNVLERNSDLAVAGITLKQARLQADLTANKQGLRTSSSVSTGHSFDLNS-----GDDSAKGLSMSAGVSYE---LDLFGKLARQTEASKWEALATEQDLQSTGQSLIATTAKLYWQLGYLNERYATAQQSLATSQKLYQLVQTQYKAGAVSGLDLTQAEQSVQSQKASLSQIEQQLVETRTAIAVLLHEPVQQLN-IQEPQRLPRTALPAIGAGLPADILSRRPDLQAAELRLRKALATKDATKASYYPSISLTSSLGSSSTSLTELLR--NP-ALTLGASLSLPFLQYNDIKKDIAISNLDYEKAIIQYRQTLYQAFADVENALSSRTELDKQVALQERNVELAEKTERLTEVRYRYGAVALKTLLDAQQTTRTARLSLVETKQSQYNAYVTLMQALGGSPVKELPQ 5AZS Chain:C ((1-450)) --------------------------------------------------CSMAPT-YERPAAPVADSWSG------------IDTLDWKSFIVDAELRRLVDMALDNNRSLRQTLLDIEAARAQYRI--QRADRVPGLNAAATGNRQRQPADLSAGNRSEVASSYQVGLALPEYELDLFGRVKSLTDAALQQYLASEEAARAARIALVAEVSQAYLSYDGALRRLALTRQTLVSREYSFALIDQRRAAGAATALDYQEALGLVEQARAEQERNLRQKQQAFNALVLLLGSD-DAAQAIPRSPGQRPKLLQDIAPGTPSELIERRPDILAAEHRLRARNADIGAARAAFFPRISLTGSFGTSSAEMSGLFDGGSRSWS-FLPTLTLPIFDGGRNRANLSLAEARKDSAVAAYEGTIQTAFREVADALAASDTLRREEKALRALANSSNEALKLAKARYESGVDNHLRYLDAQRSSFLNEIAFIDGSTQRQIALVDLFRALGGGWDEGR--

General information: TITO was launched using: RESULT: Template: 5AZS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1581 57505 36.37 134.36 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain C : 0.71 3D Compatibility (PKB) : 36.37 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.386

(partial model without unconserved sides chains): PDB file : Tito_5AZS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5AZS-query.scw PDB file : Tito_Scwrl_5AZS.pdb: