Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNAPVALTPELLTQLTAIVGENRIKTDADSLENWGKDHTKHFNPNPSVIVFPSTTEQVQEVVKLANQFNIAITPSGGRTGLSAGAVATK----GEIVISMDKMNQILEFFPADRMVRVQAGVVTEQLQNYAEEQGMYYPVDFASAGSSQIGGNIGTNAGGIKVIKYGMTRNWVLGLTVVTGKGDILRLNKGMIKNATGYALQHLFIGGEGTLGLVTEAEIKLERQPQNLQVLVLGVPDFDAVMPVLHAFQKD-IDLTAFEFFGELTMQKVLDRGHV-QRPF----------------E-TQ-CPFYVLLEFEAPYEPIIDKAMEIFEHCMEQGWVLDGVMSQSLDQVESLW-----RLREDISESIAPFIPYKNDISVLITHVPAFIREIDAIVQENYP--YFEICW-----FGHIGD-G-NLHLNILKPENLTKDEFFAKCQVVNKYVFDTVKKYDGSISAEHGVGMTKKPYLEYSRSAEEIEYMKALKKVFDPKGIMNPGKLFDL 5ADZ Chain:A ((202-658)) -----------------------------------------FERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKVVTPRGVIEKSCQG-PRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGL---AAGEDNGQRGYLLTYVIAYMRDLGLEYY--IIGESFETSAPWDRVVDLCRNVKERIRRECKEKGVQFPPLSTCRVTQTYDAGACIYFYFAFNYRGI-SDPLAVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPTNIFGNRNLL--

General information: TITO was launched using: RESULT: Template: 5ADZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2219 17376 7.83 41.47 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : 7.83 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.455

(partial model without unconserved sides chains): PDB file : Tito_5ADZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5ADZ-query.scw PDB file : Tito_Scwrl_5ADZ.pdb: