Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRQLQLDIEPQLDARISDFSGPGWGHVVDAVRQLHAGL---------------VNRFYIYGGAGTGKSHLLSAICDSYLEVGKSAIKVSLLELLD----------APIEA-------ITCLEHYDLVALDDIESISGVP----------HWQKAVFHLMNN------------HEGQLVFSSRVAPIELKLELPDLQSRLTQAVSVKVPSGSLYADRYALVTSVMARR-----------G--IHFDQQIVDYLLLHG--------PHQASVLLQTVAQLEKLLKGEK-----T--KLSNATLRQIYALIDEYQQ 1OFH Chain:C ((12-300)) --------------ELDQHIIG-QADAKRAVAIALRNRWRRMQLQEPLRHEVTPKNILMIGPTGVGKTEIARRLAKLAN---APFIKVEATKFTEVGYVGKEVDSIIRDLTDSAGGAIDAVEQNGIVFIDEIDKICKKGEYSGADVSREGVQRDLLPLVEGSTVSTKHGMVKTDHILFIASGAFQVARPSDLIPELQGRLP--IRVELTALS-AADFERILTEPHASLTEQYKALMATEGVNIAFTTDAVKKIAEAAFRVNEKTENIGARRLHTVMERLMDKISFSASDMNGQTVNIDAAYVADALGEVV----

General information: TITO was launched using: RESULT: Template: 1OFH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 970 -10396 -10.72 -50.22 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain C : 0.66 3D Compatibility (PKB) : -10.72 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.510

(partial model without unconserved sides chains): PDB file : Tito_1OFH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OFH-query.scw PDB file : Tito_Scwrl_1OFH.pdb: