Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRTLSMNYLQDARQHVLQQIRTACELAQREPETVQLLAVSKT----HPSERLREM-YAAGQRAFGENYLQEALDKIDALQDLDIEWHFIGHVQRNKTKHLAEKFDWVHGVDRLIIAERLSNQRG-DDQAALNICLQVNIDGQESKDGCAP-EDVAELVAQMSQLPKIKLRGLMVIPAPDNT-------GAFADAKKLFDAVKVQHAHPEDWDTLSMGMSSDLEAAIAAGSTMVRVGTALFGARDYSQKG 3E5P Chain:C ((12-234)) --HIDTQAITENVQKECQRL----------PEGTALFAVVKANGYGHGAVESAKAAKKGGATGFCVALLDEAIELREA-GV-QDPILILSVVDLAYVPLLI-QYDLSVTVATQEWLEAALQQLTPESNTPLRVHLKVDTG--MGRIGFLTPEETKQAVRFVQSHKEFLWEGIFTHFSTADEIDTSYFEKQAGRFKAVLAVLEE------LPRYVHVSNSATALWHPDVPGNMIRYGVAMYGLNPSG---

General information: TITO was launched using: RESULT: Template: 3E5P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1044 13106 12.55 62.71 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain C : 0.69 3D Compatibility (PKB) : 12.55 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.508

(partial model without unconserved sides chains): PDB file : Tito_3E5P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3E5P-query.scw PDB file : Tito_Scwrl_3E5P.pdb: