Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------------------------------------------------------------------------------------------------------------------------------------------------------LCTTIQKGQIFRN---ILTCMSEFYIKEEFSYTVCNGKNYASPNRTILCIWEGHIIHVRLDERCNWTRLEGDQTEELESQNVEFKVLQKCVASKYKLDPPHAWDAGHGVKLG------------------------------------------------------------------------------------------------------------------------------- 4OC8 Chain:A ((2-388)) TFFTGETLGQVDLIVDAVYAGYKTERGGMADPLVPLVGVSRQGGFRYRGTRERPTLLVLTSNLAEPEWPDQLDETTGTFIYYGDNRHPGRLLHDTPRFGNQLLRQIFDWAHLGQRHLVPPILVFTTEATGRTFRFRGLAVPGSPALAATEDLVALWKTTEGQRFQNYKAVFTILDEAVIPRAWVHAVGRGETSGLAPVAWNAWLSAGGIRPLMAPRSLLVRSKAEQL----PATPEDQALIEVIRQRYK-ENPFGFEACAGALTRLLLPDVARLDLTRPWRDGGRDGIGRLRIGQSPAAIEVDFALEAKCYGANNAVGVKEVSRLISRIKHREFGVLVTTSYVDRQAYQEVTDDGHPVILTTAQDIVGLLRSAGVRTPTQVDAWLDGITASV

General information: TITO was launched using: RESULT: Template: 4OC8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 318 -5473 -17.21 -52.62 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.55 3D Compatibility (PKB) : -17.21 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.55 QMean score : 0.161

(partial model without unconserved sides chains): PDB file : Tito_4OC8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4OC8-query.scw PDB file : Tito_Scwrl_4OC8.pdb: