Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence AILGFVNKQQAHDLLINKPDGTFLLRFSDSE-IGGITIAWKLDSP--ERNLWNLKPFTTRDFSIRSLADRLGDLS----------YLIYVF 1BG1 Chain:A ((458-561)) YIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGSTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLY

General information: TITO was launched using: RESULT: Template: 1BG1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 255 -13126 -51.47 -168.28 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -51.47 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.564

(partial model without unconserved sides chains): PDB file : Tito_1BG1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1BG1-query.scw PDB file : Tito_Scwrl_1BG1.pdb: