Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLI----ANIKESTLYPILKKLEGNSFLTTYSRE-FQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGSIRHDKN 3F8B Chain:B ((6-109)) --KEMLRAQTNVILLNVLKQGDNYVYGIIKQVKEASNGEMELNEATLYTIFKRLEKDGIISSYWGDESQGGRRKYYRLTEIGHENMRLAFESWSRVDKIIENLEAN-------

General information: TITO was launched using: RESULT: Template: 3F8B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 267 -10013 -37.50 -101.14 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain B : 0.76 3D Compatibility (PKB) : -37.50 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.376

(partial model without unconserved sides chains): PDB file : Tito_3F8B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3F8B-query.scw PDB file : Tito_Scwrl_3F8B.pdb: