Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIENKVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKELKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALPEVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDIGYDV 2QZC Chain:A ((4-208)) ---------IVGNVENLINGVGELWNKYVKHEFILKMRDGSLPLDIFRYYLIQDGKYVEDMLRALLIASSKGPIDKVTKILNLVFSS---KGLETHGKLYSKLDISRDVIVKTGYNLINYAYTRHLYYYAN-LDWNKFLVAWTPCMFGYSIVGDYVIDS-PNEVYKTWASFYASTEYKKRIEAILYALDEVSI----TEDLLNIFINSVRFEIGFWDASLR-

General information: TITO was launched using: RESULT: Template: 2QZC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 897 -131663 -146.78 -648.59 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -146.78 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.494

(partial model without unconserved sides chains): PDB file : Tito_2QZC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QZC-query.scw PDB file : Tito_Scwrl_2QZC.pdb: