Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVKDRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVERRKIIQAYGAELVLTPGSEGMKGAIAKAQEI-AAERDGFLPL-QFDNPANPEVHERTTGAEILAAFGKDG-LDAFVAGVGTGGTISGVSHALKSE--NSNIQVFAVEADESAI----LSGE--KPGPHKIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIEVAKKLG-TGKKVLALAPDNGERYLSTALYEL 1OAS Chain:B ((3-311)) --IYEDNSLTIGHTPLVRLNRI---GNGRILAKVESRNPSFSVKCRIGANMIWDAEKRGVLKPGVELVEPTNGNTGIALAYVAAARGYKLTLTMPETMSIERRKLLKALGANLVLTEGAKGMKGAIQKAEEIVASDPQKYLLLQQFSNPANPEIHEKTTGPEIWE--DTDGQVDVFISGVGTGGTLTGVTRYIKGTKGKTDLITVAVEPTDSPVIAQALAGEEIKPGPHKIQGIGAGFIPGNLDLKLIDKVVGITNEEAISTARRLMEEEGILAGISSGAAVAAALKLQEDESFTNKNIVVILPSSGERYLSTALF--

General information: TITO was launched using: RESULT: Template: 1OAS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1738 8580 4.94 28.89 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain B : 0.88 3D Compatibility (PKB) : 4.94 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.88 QMean score : 0.484

(partial model without unconserved sides chains): PDB file : Tito_1OAS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OAS-query.scw PDB file : Tito_Scwrl_1OAS.pdb: