Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MINMEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTTFSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVD--HISNAQINASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL 1QD1 Chain:B ((77-142)) ----------------------------------HHGEHPRMGALDVCPFIPVR-GVT-------MDECVRCAQAFGQRLAEELGVPVYLYGEAARTAGRQSLPALRA------------------------------------

General information: TITO was launched using: RESULT: Template: 1QD1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 164 -13937 -84.98 -217.76 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.56 3D Compatibility (PKB) : -84.98 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.56 QMean score : 0.142

(partial model without unconserved sides chains): PDB file : Tito_1QD1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QD1-query.scw PDB file : Tito_Scwrl_1QD1.pdb: