Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MELRRPRLADKKAVLDMMTEFEKFQSP-HDGGFWDTENF-VYEDWLESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRPSERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVERYWIEVANE 4JWP Chain:A ((24-166)) LLIRHATEADLPALLAIYNDAVENTLAIWNE---TLVDLENRHQWLENRNR------------DGFPVLVAEREGQVVGYASYGPFRPFEGFRHSSELSVYVASNARGGGIGRTLLAELIEEARERKVHVLIAGIEAGNAASIALHRSQGFEECGTLK------------

General information: TITO was launched using: RESULT: Template: 4JWP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 565 -122 -0.22 -0.87 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -0.22 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.540

(partial model without unconserved sides chains): PDB file : Tito_4JWP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4JWP-query.scw PDB file : Tito_Scwrl_4JWP.pdb: