Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIMQIRQFQAQRMQAPRDFTPIENTPICVEIGAGKGKHALLFSGQNPQHTLYAIERTREKFLAMQKQHGLEPRDNLIPVHADALPWVVHALYPAQVEHFFILYPNPEPH--NPAQRWLNMPFFEFLLSRLKTGGTITLAGNIPEYIEEAEQQLLNVWKLPYQ------KEKIAQTSARTHFEIKYLERGELCQQLIMTKPEGYNTRFDEFAPLQGQIHVE 1YZH Chain:B ((39-213)) ---------------------GNDNPIHVEVGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD-YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFEYSLVSFSQYG-MKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAE----------------------

General information: TITO was launched using: RESULT: Template: 1YZH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 737 -24239 -32.89 -145.14 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain B : 0.66 3D Compatibility (PKB) : -32.89 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.378

(partial model without unconserved sides chains): PDB file : Tito_1YZH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YZH-query.scw PDB file : Tito_Scwrl_1YZH.pdb: