Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTFQYQVLANQLAHRIYQDELKPHQKLISLRDFARQQGISLSTAKSCYELLEARGLIYVKPKSGYFVVARTPSSPIPDSPDFLSLPRHVSNLELHNQIQKAALQSHLVPLGSIQLTPHFIPVEGLRRSIQRALKNCQPQDFLYCNKQGHEQLRKALSDHWRE-DGIYIAPEDIFITNGCMPALSLVIQKLTEVGDSILIPTPTYNGHLQLLASLKRQIVEIPADHRGIDLERLESLMQQ-----GLAKVCLMTANYQNPLGYCFSNAEKEKIAELAAKYQCFIIEDDIFGECGYSSERPLPIRYWDREGYVIWCGSVSKSLSSAYRVGWFCLTTKLEHLKLEL-LVSNIGVNTPLQLGLADFIYSRGYREHLEQLRPNLMRQVEEYRSCILKAFEDIPIALSQPEGGYALWIQLPKSVDSLALYYTAQAQGITVVPGH------------------ELTADVRQAIMSLAGWSRQQMQTVS 3AOW Chain:A ((75-447)) -------------------------------------------------------------------------------------------------------TSDIISLAGGLPNPKTFPKEIIRDILVEIMEKYADKALQYGTTKGFTPLRETLMKWLGKRYGISQ-DNDIMITSGSQQALDLIGRVFLNPGDIVVVEAPTYLAALQAFNFYEPQYIQIPLDDEGMKVEILEEKLKELKSQGKKVKVVYTVPTFQNPAGVTMNEDRRKYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEGRVIYLGTFSKILAPGFRIGWMVGDPGIIRKMEIAKQSTDLCTNVFGQVVAWRYVDGGYLEKHIPEIRKFYKPRRDAMLEALEEFMPEGVK-WTKPEGGMFIWVTLPDGIDSKKMLERAIKKGVAYVPGEAFYAHRDVKNTMRLNFTYVDEDKIMEGIKRLAETIKEELK---

General information: TITO was launched using: RESULT: Template: 3AOW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1909 9047 4.74 26.00 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : 4.74 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.537

(partial model without unconserved sides chains): PDB file : Tito_3AOW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3AOW-query.scw PDB file : Tito_Scwrl_3AOW.pdb: