Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTKLAILILSLAFFGSAHADVKTLEQNLKTNYPDLPVKGVYQS--PVAGIYEVYTS-GRIVYTNQDAKYFFVGNLVDIKQQKNMTEERIAE-----LGKIDVKSLPLNQAI-KYVKGKGERTLYIFSDPDCPYCQRLEQNMVGV---DNVTVYVFLYPLTSLHPNAEKVSNQIWCSKNPSEAWTNYMLNRK---LP-AA-GKS-CTSPVQKNIALGQKLNIDGTPTLFLQDG----QKISGVPGDAKQIEELLQSVK 1V58 Chain:B ((4-230)) ----------------------PAPVKAIEK--QGITIIKTFDAPGGMKGYLGKYQDMGVTIYLTPDGKHAISGYMYNEK-GENLSNTLIEKEIYAPAGREMWQRMEQSHWLLDGK-KDAPVIVYVFADPFCPYCKQFWQQARPWVDSGKVQLRTLLVGV--IKPESPATAAAILASKDPAKTWQQYEASGGKLKLNVPANVSTEQMKVLSDNEKLMDDLGANVTPAIYYMSKENTLQQAVGLPD-QKTLNIIMGN--

General information: TITO was launched using: RESULT: Template: 1V58.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 875 28830 32.95 140.63 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain B : 0.68 3D Compatibility (PKB) : 32.95 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.538

(partial model without unconserved sides chains): PDB file : Tito_1V58.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1V58-query.scw PDB file : Tito_Scwrl_1V58.pdb: