Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIATFNKSKTALTINRQEFKLALGKIDAGIEKQIVSLKKAKQSYNAAEMAREVISEANIFEAIIEGF---NEAEGTNLKL-----ADITN----LEVAQGWIDDFLEKYSEV 3QI3 Chain:B ((362-424)) ---------------------------------------------ATDMARHA-EIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEY---

General information: TITO was launched using: RESULT: Template: 3QI3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 90 -743 -8.25 -14.56 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain B : 0.67 3D Compatibility (PKB) : -8.25 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.267

(partial model without unconserved sides chains): PDB file : Tito_3QI3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QI3-query.scw PDB file : Tito_Scwrl_3QI3.pdb: