Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MK--IVILNKPYDVLSQFRKDEAHMTVSDFVDDPTLRIAGRLDMDSEGLVFLT--DHGGLNQFITNPANKKYKTYLV--------QVDGDVTEEA-----LEQLRKGVELNDGMTL------------PAKAIKVSEPEWLWDRDPPVRYRASI-----PTSWIEISICEGRNRQVRRMTSAVGFP------TLRLIRTKIGTIDLVQ-LGLQPGETKEIEPLLYPDFKDVPAEQPYRSRSYVRKPGGTGGKPMVRKNKDGSAKKSGTKRIWQMDESE--------KPRRKTNGTTRPNTKAPRGRSRNSR 1R3E Chain:A ((1-309)) MKHGILVAYKP----KGPTSHDVVDEVRKKLKTRKVGHGGTLDPFACGVLIIGVNQGTRILEFYKDL-KKVYWVKMRLGLITETFDITGEVVEERECNVTEEEIREAIFSFVGEYDQVPPAYSAKKYKGERLYKLAREGKIINLPPKRVKIFKIWDVNIEGRDVSFRVEVSPGTYIRSLCMDIGYKLGCGATAVELVRESVGPHTIEESLNVFEAAPEEIENRIIP-LEKCLEWLPRVVVHQESTKMILNGSQIHLEMLKEWDGFKKGEVVRVFNEEGRLLALAEAERNSSFLETLRKERVLTLRKVFNTR

General information: TITO was launched using: RESULT: Template: 1R3E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1281 57569 44.94 224.88 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : 44.94 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.256

(partial model without unconserved sides chains): PDB file : Tito_1R3E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1R3E-query.scw PDB file : Tito_Scwrl_1R3E.pdb: