Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence PEHCFVRILKYEIPIHGDGYLVGSDVNWWVGNQKVDFHINNDCTIQRRGGTQEKKPYRLDSISTLGEDLPKGFDFILFRESKIDEFLAQGGVTKRILGSMIL----------- 1B6A Chain:? ((375-448)) -------------------------------------HDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLDR-LGESKY-LMALKNLCDLGIVDPYPPLC

General information: TITO was launched using: RESULT: Template: 1B6A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 165 -21016 -127.37 -333.58 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.54 3D Compatibility (PKB) : -127.37 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.54 QMean score : 0.340

(partial model without unconserved sides chains): PDB file : Tito_1B6A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1B6A-query.scw PDB file : Tito_Scwrl_1B6A.pdb: