Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLLLKVRQNVPQVQSIKTSLKKRAGQKIPHMLSNASDLFFRGSEIALSGKTPFDVIYKHEIISLRHYRIETEASAHKHRVPLVIVPPLAVNMLIYDLFPTRSLIRYFLDQGFEVYLIDWGVPTRNQAK---YNFGTYVKVFMPEMLKQVRIHSGQQQLSLHGWSLGGALSLCYTALFKDKDIKNLMILASPIDTHKAGYMGKLYGSLTKPAQWVRKHTPFRIRQHVPSEVFHIHGWQNTLGFKLTAPIGNLKTYWQLLKNLDNREFIVDHATSSSFIDNMLAYPGGVMRDIILRFWIDNELSTGVIKFGELTAYLKDIDCSVLAVGGDTDIIVTADAVKPLMDLISSQDKTFKTVPSGHMGVVSGSQAPTSVWPEMSNWLAMRSD 3OM8 Chain:B ((7-266)) ------------------------------------------------------SFLATSDGASLAYRLDGA-----AEKPLLALSNSIGTTLHMW-----DAQLPALT-RHFRVLRYDARGHGASSVPPGPYTLARLGEDVL-ELLD----ALEVRRAHFLGLSLGGIVGQWLALHAP-QRIERLVLANTSAWLGPAAQWDE-------------RI----A-----A---VLQAEDMSETAA-----GFLGNWFPPALLERAEPVVE------RFRAMLMATNRHGLAGSFAA-----------VRDTDLRAQLARIERPTLVIAGAYDTVTAASHGELIAASIA--GARLVTLPAVHLSNVE---FPQAFEGAVLSFLGA---

General information: TITO was launched using: RESULT: Template: 3OM8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1501 -96118 -64.04 -374.00 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain B : 0.63 3D Compatibility (PKB) : -64.04 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.419

(partial model without unconserved sides chains): PDB file : Tito_3OM8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OM8-query.scw PDB file : Tito_Scwrl_3OM8.pdb: