Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQVYLVGGAVRDYLLGHSYQEKDYVVVGATPEHMLAQGFQPV------GKDFPVFLH--PETKEEYALARTERKSGQGYHGFQFFTDTTVSLEDDLIRRDLTINAIAMDQD----GKIYDPYGGQNDLENKILRHVSE-AFAEDPLRVLRVARFAARYFPYGFQIAPETLQLMQTMADSGELDALTPERVWKETSRALMENHADIYFQTLRDCGALKHLFPEIDALFGVPQRPEYHPEVDCGIHTLMSLQQACKSNYSLDVRFAVLVHDLGKALTPAKELPRHIMHEERGIKPVTQLCERLRVPTQTKQLALSVCKEHLKC--HQIMSLKPGTLWRLLQRLDVLRRPERVEAFVQACECDAKGRLGLEDRPYPQAQYMREAMQIVRSIKVQDLPENI-KGAEIGEMLIQYRIEALAEFKNQHQSLSHS 4WBY Chain:A ((26-396)) -RAYIVGGVVRDILLGKEVWDVDFVVE-GNAIELAKELARRHGVNVHPFPEFGTAHLKIGKLKLEFATARRE----------------PASLKEDLIRRDFTINAMAISVNLEDYGTLIDYFGGLRDLKDKVIRVLHPVSFIEDPVRILRALRFAGRL---NFKLSRSTEKLLKQAVNLGLLKEAPRGRLINEIKLALREDRFLEILELYRKYRVLEEIIEGFQWNEKVLQK-LYALRKVVDWHALEFSEER---IDYGWLYLLILISNLDY-------------------ERGKHFLEEMSAPSWVRETYKFMKFKLGSLKEELKKAKENYEVYRLLKPLHT----SVL---LLLML-EEELK-------EKIKLYLEKLRKVK----------GLKGKE-LGERIEELKREIMNK-----------

General information: TITO was launched using: RESULT: Template: 4WBY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1487 23478 15.79 70.93 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 15.79 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.461

(partial model without unconserved sides chains): PDB file : Tito_4WBY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4WBY-query.scw PDB file : Tito_Scwrl_4WBY.pdb: