Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAKDEYFLETSSSKRIIVCLLDVFVSISTIRYLFFIARCENMFHNREVRKKLSNGGQKMKTVILAEKPSQAKAYAETFQQQ--KRH---EGYYEIS-DP-LFAG---EVTITYGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMD--KR---AQFSIVKRELQSADTIIIATDGDREGEAIAWSIIRQANAF-----SKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYFPKYKEAQARQNADWLIGMNGSPLYSLLLQRKGI---DGSFSLGRVQTPTLYMIYQLQEEIKHFKKETYFEGEGLITTNKG-QFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEVTKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITENEH--QYLVKHLQNYKKFLGIEEVQT-T-EIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFAKLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILRIKSKKKEAQTLPPIVENEEAEV-ELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEAQEILKEVEGIGTEATRANIIENLKQKHYIEVN-KNEITVTPKGITLCKAVANE-PLLTSAEMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIKAMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSKGKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENEVE 5GVC Chain:A ((2-602)) --------------------------------------------------------GHMKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMTLDFLG-------KWDKVDPAE---LFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDH--NEALSVDARQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETYWVLQAKVNTDKDRSLLLDWDR-VRVFDREIAQMFLNMT--KLE-KEAQVEATSRKEKAKQRPLALNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANHP---YWADTVKRLLAEGINRPRKGHD--AGDHPPITPMKSATE----AELGGDAWRLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVP-LEESLPTCQRGDAFPVGEVKMLEKQTNPPDYLTEAELITLME-----------------KHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNLGIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDS---------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5GVC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2931 91906 31.36 162.09 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 31.36 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.415

(partial model without unconserved sides chains): PDB file : Tito_5GVC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5GVC-query.scw PDB file : Tito_Scwrl_5GVC.pdb: