Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYGNELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNRMTYYVSKLLVTLLITTL-GVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLLLILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWLMYTDFAQQATYSQAPKMIL-VSLVTIVVSSALGMFIFQKSDIK-------- 1Q3K Chain:A ((1-259)) -SKSVFVGELTWKEYEARVAAGDCVLMLPV-------GALEQHGHHMCMNVDVLLPTAVCQRVAERIGA-LVLPGLQYGYKSQQKSGGGNHFPGTTSLDGATLTGTVQDIIRELARHGVRRLVLMNGHYENSMFIVEGIDLALRELRYAGI--HDFKVVVLSYWDFVKDPAVIQRLYPEGFLGWDIEHGGVFETSLMLALYPDLVDLERVVDHPPATFPPYDVFPVDPARTPAPGTLSSAKTASREKGELILEVCVQGIADAIGQEFPPT

General information: TITO was launched using: RESULT: Template: 1Q3K.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1353 -153769 -113.65 -617.54 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -113.65 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.147

(partial model without unconserved sides chains): PDB file : Tito_1Q3K.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q3K-query.scw PDB file : Tito_Scwrl_1Q3K.pdb: