Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPRIPVINTSHLDRIDELLVDNIDTGEFKLHRSVFTDEALFDLEMKYIFEGNWVYLAHESQIPNNNDYYTTYIGRQPIIIARNRNGELNAMMNACSHRGAQLCRYKRGNKATYTCPFHGWTFNNSGKLLKVKDPTDAGYS------DCFNQDGSHDLKKVARFESYKGFLFGSLNPDVPSLEEFLGETTKIIDMIVDQSEHGLEVL-RGSSTYTYEGNWKLTAENGA-DGYHVSAVHWNYAATTQHRKETQAADNIRAMSAGSWGKQGGGSYGFENGHMLLWTQ-WANP--E-DRPNFPK-AD------EYTEKYGEAMSKWMIERSRNLCLYPNVYLMDQFGSQIRVLRPLSVNRTEVTIYCIAPKGEA-R--ARRIRQYEDFFNASGMATPDDLEEFRACQAGYAGIALEWNDMCRGSKHWIYGPDDAANEIGLKPMLSGI--KTEDEGLYLAQHQYWLKTMKHAIATEKEIADQGETA 3GZX Chain:A ((20-454)) ----------TPDAIRALVDQ----DNGKLDARIYADQDLYQLELERVFGRSWLMLGHETHIPKIGDYLTTYMGEDPVIMVRQKDQSIKVFLNQCRHRGMRIVRSDGGNAKAFTCTYHGWAYDIAGNLVNVPFEK-EAFCDKKEGDCGFD-KADWGPLQA-RVETYKGLVFANWDPEAPDLKTYLSDAMPYMDVMLDRTEAGTEAIGGI-QKWVIPCNWKFAAEQFCSDMYHAGTMSHLSGVLAGLPPEMDLTQ----IQLSKN---GNQFRSAWGGHGAGWFINDSSILLSVVGPKITQYWTQGPAAEKAARRVPQLPI-L-DMFGQHMTVFPTCSFLPG-INTIRTWHPRGPNEVEVWAFVLVDADAPEDIKEEFRLQNIRTFNAGGVFEQDDGENWVEIQRVMRGH---KAKSTSLCAKMGLNVPNKNNP--AYP---GKTAYVYAEEAARGMYHHWSRMMSEPSWDT----------

General information: TITO was launched using: RESULT: Template: 3GZX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2120 -29392 -13.86 -71.51 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -13.86 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.434

(partial model without unconserved sides chains): PDB file : Tito_3GZX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3GZX-query.scw PDB file : Tito_Scwrl_3GZX.pdb: