TITO

Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)

Input alignment information:

Query sequence

--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYNRSVMINLNVRSEMALQILQKQLDESSHCPLCQASMYWVDAEQFEQDVQFHECSHCQHRVFKDTKMTCHCDQCTKQRKKLLQQTRLQEQRQFKLKDQPQRSLEQLSFLHKLFLLSLLDDYARDDVAHDEYIHWDQIKYQPITPNWMFQSHLIKQLHKDGILNAQDQTDEPQCFYLNIRLDGYSDPSLFSVAQQLRHWFYENLSLGIPFR-SADEVKDVLFQVLYQEIIQFTQFYCRTWGIQIAGSSNFQAFCYRLMDSLAIGQIYYLIQTALEYLYKQKALQPRNEKFINTNLLKKTLEQYRERALAEKWETSMLPRPYNIPYSKMSHILFNRFLGYDEQIFVQPVWKAWRKIEPRLNFYSVKRCMYCGSNDLSVDYDAADYVSLICQNCKHQDHYFTR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

5T8V Chain:A ((4-1456))

GESLDLRQRANVALHELKAYLQAAFQAVDRAIAQKSSNEMAIFLSETEATLAAPTQTKLQSALKKTIELNCFMTVPLDDLIYLLRLCDSALRQTESLDFSVQTSWGAQDVEQWLELLPNLEAAIRAARTSMRIMCGGREEKQLYSENAIEQALSLCKRLIDGIIMPLAELRNTSDTEELFKALSSCKRRILPLMTDAQKLLSMMSELIAKVDTSETVTNALEFAASQLLFIETANAERDSVIETQKFDGFRLVAMDMICQIFLLNPSQRQGIIDEILTSLEKLPLGKRARTFKLADGSSIQPVSALIMRLVQTSAGIIQSEAQGASQHSTAIRDLDTISTPLLETARNNASYVIKFIVNRALNSPYRNLLDLFVEDFITCLDNPDWPAAELLLRLLMLMMVGLVENDKSSIMAKNMALELLGTMCAAISKLRGHVRKMASALEADELSLFLSDLAASALELKSRPEHMVAWTGPYRATLEYLQSRSNEDAQLSSAMTFIISEWGSKICTCYDGYQDDVLERDQELGRLAYRLREMILDRKWLSTEYTYKDVSPLQAKLSYSIILLRSQFCEAFGAILNILLNSMASDQPTVRSKSLKSINQVMEADPTILDGD--SVVVQLILRSSSDSS----------TQVRDSALGLISKCISLRPALEEKMTETVVNRFSDAGPGVRKRAMKLAKDIYLRN---SNRVLRSAIANGLLHRV----------QDPEESVRDLARQVIEEIWFAPSLSEHVILMVQTVKRG--NVANVLDKVLQALLS--PSSKTSQASMEVCRKLVGSMFDLIDNNDASAPSGRDVLQVLMIFAKAEASLFTFEQLRLLRPYIASIGTSE----DLTVSRAVVVIYRRVLPQLSSAHAQFLTDVRKELL---PVVAKVPRALLDDVMACLWIISTLLGTY----EPLARLVISSLKGIQKTRASAQVQPLDQLKIRQFDRYSLIVGMAGKHCNLDSHHE------------MFKEHFPKFSGASVSKLMVDIVVPFAAPSWPLDVRKPALDCVGLVCQSSPRNYVAANVYTAFQQVFDDQIPILETMVLRSLKEFLFSEEKRSETNYDDVASATTHRFLKDITRIATSTQDDHAFLAVEVLASINRQGLVHPKETGVTFITLATSTHPRISELAFLEHKALHTKHETVIEREYAKAIQSIFAYQRDIVKDPRGATTNPFTPKLHLFMEVLKISKAKNRVKFLEKLVSQIDFDIAKLELPPHVQYSRFIIENLAFFEYVTVGEIHSLVAAMERLVASTGASVAQVIESEVRLRQLTAASMILLAIWEVRTYLRRLYSLARPPVKVQGVTGDKVWEEINNIMGALSGGRERMVRACKDLVELMSID

General information:

TITO was launched using:	RESULT:
Template: 5T8V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output	Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1420 20665 14.55 59.38 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.52 3D Compatibility (PKB) : 14.55 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.52 QMean score : 0.184

(partial model without unconserved sides chains):
PDB file : Tito_5T8V.pdb:

(Unconserved sides chains are recalculated) :
Sequence: align-5T8V-query.scw
PDB file : Tito_Scwrl_5T8V.pdb: