Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKMLMALSLTGALLGGTAAWAEETVTTPTSEVTATSTSEAPATIAAAPAAEETPAAPTPTAKLDTGDTSWILISTALVLLMTIPGLALFYGGMVRKKNVLSTMMFSLSAAILVSLLWVIAGYSIAFSGT-GAYFGDLSKAMLNGVAFDALSGTIPESLFVIFQMTFAIITVAILSGSIADRMKYSAFMAFIAIWVLVVYAPITHWVWAADGWLFKAGALDFAGGTVVHINSGVAGLVAAYMLGKR-IGLGRESMAPHNLTLTVIGASLLWVGWFGFNGGSALGAGARASMAILVTQVAAAAAAFSWLVVERMIRGKASVLGGASGAVAGLVVITPAAGFVGVGGALVMGLIGGVVCFWGITALKRLLKADDALDAFGLHAVGGIVGAILTGVFYSDEIIKAANVALAPTFAGQLWVQVEGVLATMVYSGIATFIILKVIDLIIGLRVNSDDERMGLDLSQHGERIE 2B2H Chain:A ((2-390)) ----------------------------------------------------------------SDGNVAWILASTALVMLM-VPGVGFFYAGMVRRKNAVNMIALSFISLIITVLLWIFYGYSVSFGNDISGIIGGLNYALLSGV-------KGEDLLFMMYQMMFAAVTIAILTSAIAERAKVSSFILLSALWLTFVYAPFAHWLWG-GGWLAKLGALDFAGGMVVHISSGFAALAVAMTIGKRAGFE-EYSIEPHSIPLTLIGAALLWFGWFGFNGGSALAANDVAINAVVVTNTSAAVAGFVWMVIGWIK-GKPGSLGIVSGAIAGLAAITPAAGFVDVKGAIVIGLVAGIVCYLAMDFRI-KKKIDESLDAWAIHGIGGLWGSVAVGILANPEVNGY--AGLLFGNPQLLVSQLIAVASTTAYAFLVTLILAKAVDAAVGLRVSSQEEYVGLDLSQHEEVAY

General information: TITO was launched using: RESULT: Template: 2B2H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2410 -363517 -150.84 -939.32 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -150.84 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.413

(partial model without unconserved sides chains): PDB file : Tito_2B2H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2B2H-query.scw PDB file : Tito_Scwrl_2B2H.pdb: