Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MITTSVTEAAECLQQGQVLAYPTEAVWGLGCDPFNEQAFQKILELKQRPIEKGVILLAGHISQVEHLLTSLPQTTQQEIIDCWTNHQPSERATTWLLPADQ-HIPSWIKGEHPLVAVRVTTHPLCVALCNAFHGFIVSTSANPSGQEPAHSLQDACQYFGS-QLNYLNGDL-GQSQQPSRIINALTGEVIRP 3TTD Chain:A ((111-284)) --EAALQAAIAQLKMGNIVAIKGIGGFHLACDARNSNAVATLRARKHRP-AKPLAVMLPVADGLPD-------AARQLLTT-PAA------PIVLVDKKYVPELCDDIAPGLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLSGKPPAISNEQALEDLQGIADGFLIHNRDIVQRMDDSVVRESG-EMLRR

General information: TITO was launched using: RESULT: Template: 3TTD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 865 -61073 -70.60 -357.15 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -70.60 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.428

(partial model without unconserved sides chains): PDB file : Tito_3TTD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TTD-query.scw PDB file : Tito_Scwrl_3TTD.pdb: