Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTRIALLDYGMGNLHSAAKALEYVGATVDVT--NDP--KLIAQADKIVFPGVGAMRDCMQGMREAGIDEVVRK-AAFNKPVLAICVGMQALLQSSEENGGVDALGIFDGVVKHFPQMEGLKVPHMGWNQVHQMDPSHPMWNNIEQDARFYFVHSYYVEPKDE-NLVAATCEYGVNFCTAI-HKDNLFATQFHPEKSHTAGLQLLKNFVEWNI 1GPW Chain:F ((1-198)) -MRIGIISVGPGNIMNLYRGVKRASENFEDVSIELVESPRNDLYDLLFIPGVGHFGEGMRRLRENDLIDFVRKHVEDERYVVGVCLGMQLLFEESEEAPGVKGLSLIEGNVVKLRS---RRLPHMGWNEVIFKD----TF----PNGYYYFVHTYRA--VCEEEHVLGTTEYDGEIFPSAVRKGRILGFQFHPEKSSKIGRKLLEKVIECSL

General information: TITO was launched using: RESULT: Template: 1GPW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain F - contact count / total energy / energy per contact / energy per residue : 1082 -4366 -4.03 -22.86 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain F : 0.76 3D Compatibility (PKB) : -4.03 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.439

(partial model without unconserved sides chains): PDB file : Tito_1GPW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GPW-query.scw PDB file : Tito_Scwrl_1GPW.pdb: