Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKNSVQYLFSCLLGMTTFSVGITPTSAGQMYIYQDKNGSTLLTNRKSYDHSLKKVKVTYYPDSNIHSYSNWGTSEASVLPSYSKNKNAFDHIIKQAAQQHGVSEGLIKAVMHTESGFNVNVRSPVGAQGLMQLMPATARRFNVSNAYDPQQNIFAGAKYLSWLLKRFNG------NTQMALAAYNAGEGNVDKYG--------------GI----P----------------PFRETQDYVRRVTSRYQNLYSSGVGLSSFSNSSISAQAINQPAIPHSTSTQVSAQPIKYSSSRQIVTLPDGTYTDAPTGTYVTNNATAIAHIRIE 4OZ9 Chain:A ((257-424)) --------------------------------------------------------------------------------------PRYESHFKQSGKQLDTDWRLLAAIGYQESLWQPGATSKTGVRGLMMLTNRTAQAMGVSNRLDPKQSIQGGSKYFVQIRSELPESIKEPDRSWFALAAYNIGGAHLEDARKMAEKEGLNPNKWLDVKKMLPRLAQKQWYAKTRYGYARGGETVHFVQNVRRYYDILTWV-------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4OZ9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 543 -34104 -62.81 -266.43 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -62.81 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.608

(partial model without unconserved sides chains): PDB file : Tito_4OZ9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4OZ9-query.scw PDB file : Tito_Scwrl_4OZ9.pdb: