Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --YGDCFIGLYEKGGRNPNHIAGTEADESGTFEVLHENYKIRVKIFKCVKQHVYDSTPSGTEIRVIPSVG-----YDPNKRQTAPRPAPRPAPR---PAPRRTQNAAGHR 1V6E Chain:A ((1-95)) GSSGSSGVMV---------FISSSLNSFR--SEKRYSRS-LTIAEFKCKLELVVGSPASCMELELYGADDKFYSKLDQEDALLGSYP-VDDGCRIHVIDHSGSGPSSG--

General information: TITO was launched using: RESULT: Template: 1V6E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 363 17173 47.31 202.03 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 47.31 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.402

(partial model without unconserved sides chains): PDB file : Tito_1V6E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1V6E-query.scw PDB file : Tito_Scwrl_1V6E.pdb: