Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEELLAEFSNY-GIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTEADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGLIGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVADLTVFLAGQD--YLTGQVIAIDGGLSM 4I08 Chain:B ((8-250)) MNLEGKVALVTGASRGIGKAIAELLAERGAKVIGT---ATSESGAQAISDYLGDNGKGMALNVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNTVAPGFIET--TKALNDEQRTATLAQVPAGRLGDPREIASAVAFLASPEAAYITGETLHVNGGMYM

General information: TITO was launched using: RESULT: Template: 4I08.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1314 -49067 -37.34 -206.16 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain B : 0.86 3D Compatibility (PKB) : -37.34 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.86 QMean score : 0.575

(partial model without unconserved sides chains): PDB file : Tito_4I08.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4I08-query.scw PDB file : Tito_Scwrl_4I08.pdb: