Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHCLMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIK---VLHGPTVTD----WGTESLLVQGPAGLVLDFYRMK 1QTO Chain:A ((4-121)) FLGAVPVLTAVDVPANVSFWVDTLGFEKDFGDRDFAGVRRGDIRLHISRTEHQ---IVADNTSAWIEVTDPDALHEEWARAVSTDYADTSGPAMTPVGESPAGREFAVRDPAGNCVHFTAG-

General information: TITO was launched using: RESULT: Template: 1QTO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 455 -41224 -90.60 -371.38 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -90.60 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.524

(partial model without unconserved sides chains): PDB file : Tito_1QTO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QTO-query.scw PDB file : Tito_Scwrl_1QTO.pdb: