Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAIQEIRHPLIRHKLGLLRRADISTKNFRELAQEVTMLLTYEATKDLPVVDCEIE-----GWAGNVTTQRIAGKKITIVPILRAGIGMLDGVLNLIPSAKVSVLGLERDEATLEVRTYYKKLVPDVANRIAMIIDPMLATGNSLVAAIDVLKASGCKDIRVMV--LVAAPEGIAKVEAAHPDIQLYTASIDNGLNEHGYIVPGLGDAGDKIFGSVQKD 1JLS Chain:A ((44-242)) ----------LRAMMTIIRDKETPKEEFVFYADRLIRLLIEEALNELPFQKKEVTTPLDVSYHGVSFYSKICG-----VSIVRAGESMESGLRAVCRGVRIGKILIQRD----EPKLIYEKLPADIRERWVMLLDPMCATAGSVCKAIEVLLRLGVKEERIIFVNILAAPQGIERVFKEYPKVRMVTAAVDICLNSRYYIVPGIGDFGDRYFGT----

General information: TITO was launched using: RESULT: Template: 1JLS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 888 -41765 -47.03 -222.15 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -47.03 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.433

(partial model without unconserved sides chains): PDB file : Tito_1JLS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JLS-query.scw PDB file : Tito_Scwrl_1JLS.pdb: